Table 5.

Change in motor M-wave and sensory nerve action potential (SNAP) amplitudes during treatment (mean ± SD)

Δ evoked amplitudePlacebo, n = 35150 mg bid, n = 37300 mg bid, n = 44600 mg bid, n = 37p Value*
* Adjusted for Williams’ test.
SNAP median (μV)0.59 ± 0.98−0.60 ± 0.81−0.50 ± 0.990.84 ± 0.730.37
SNAP sural (μV)−0.59 ± 0.49−1.24 ± 0.51−1.15 ± 0.360.47 ± 0.620.36
M-wave peron (mV)−0.32 ± 0.210.03 ± 0.19−0.48 ± 0.19−0.06 ± 0.190.45
Overall rank score0.49 ± 0.030.48 ± 0.030.47 ± 0.020.56 ± 0.030.13