Table 3.

Factors influencing ALS survival: Multivariate analysis (Cox model)*

Variablep ValueRisk ratio95% CI
* In this analysis, PEG and noninvasive ventilation were included as time-dependent variables.
CI = confidence interval; FVC% = forced vital capacity percent of predicted; PEG = percutaneous endoscopic gastrostomy.
All patients
Age at onset, y0.0003
<651
≥652.031.65–2.46
FVC% at diagnosis0.005
≥651
<651.751.41–2.00
Type of ALS at onset0.009
Spinal1
Bulbar1.691.38–2.06
PEG0.02
Yes1
No1.551.28–1.88
Spinal patients
Age at onset, y0.001
<651
≥652.451.85–3.24
FVC% at diagnosis0.008
≥651
<651.731.45–2.61
Bulbar patients
PEG0.02
Yes1
No1.831.39–2.40
Age at onset, y0.026
<651
≥651.861.42–2.42
FVC% at diagnosis0.035
≥651
<651.681.24–2.53