Table 1.

Characteristics of 160 patients with cerebral venous thrombosis: Comparison of patients with isolated raised intracranial pressure (Group I) and patients with other neurologic symptoms and signs (Group II)

CharacteristicsGroup I: Patients with isolated raised intracranial pressureGroup II: Patients with other neurologic symptoms and signsp Value
* p Value calculated using chi-square test. Only statistically significant differences between Group I and Group II are indicated in the table.
Number (%) of patients59/160 (37)101/160 (63)
Mean age (range), y36 (11–71)42 (20–77)
Sex ratio (F/M)33/2661/40
Clinical presentation, n (%)
Intracranial hypertension59 (100)83 (82)
Seizures058 (57)
Focal signs077 (76)
Altered consciousness045 (45)
Site of sinus occlusion, n (%)
Superior sagittal sinus32, 7 isolated (54)63, 15 isolated (62)<0.05
Lateral sinus*47, 17 isolated (80)61, 12 isolated (60)
Straight sinus8 (13.5)15 (15)
Deep cerebral veins3 (5)9 (9)
Cortical veins*2 (3.5)38 (38)<0.001
Cavernous sinus02, 5 isolated (2)
Cerebellar veins02 (2)
CT with contrast, n (%)50/59 (85)86/101 (85)
Normal*27 (54)14 (16)<0.001
Abnormal23 (46)72 (84)
Small ventricles*15 (30)44 (51)<0.05
Empty triangle sign12 (24)20 (23)
Parenchymal hypodensity*5 (10)38 (44)<0.001
Parenchymal hyperdensity*1 (2)32 (37)<0.001
Cortical enhancement6 (12)18 (21)
Lumbar puncture, n (%)44/59 (75)70/101 (69)
Opening pressure >200 mm25/32 (78)15/21 (71)
Normal CSF content*33/44 (75)29/70 (41)<0.001
Abnormal CSF content11/44 (25)41/70 (59)
Protein, mg/dL [range][10–222]: >50 in 5 (8.5)[10–655]: >50 in 27 (38.5)
White cells/mm3 [range][0–280]: >4 in 3 (5)[0–1,600]: >4 in 28 (40)
Red cells/mm3 [range][0–4,800]: >50 in 9 (15)[0–8,500]: >50 in 26 (37)
Etiologic factors, n (%)
Local causes7 (12)12 (12)
Surgery1 (1.5)0 (0)
Inflammatory diseases*18 (30.5)12 (12)<0.005
Infectious diseases2 (3)7 (7)
Cancer1 (1.5)7 (7)
Pregnancy0 (0)3 (3)
Postpartum state1 (1.5)12 (12)<0.05
Coagulopathies11 (19)13 (13)
Oral contraception7 (12)10 (10)
Unknown11 (19)25 (25)
Prognosis, n (%)
Complete recovery*55 (93)68 (67)<0.001
Optic atrophy3 (4.5)1 (1)
Neurologic sequelae*0 (0)26 (26)<0.001
Death1 (1.5)6 (6)