Table 1.

Clinical characteristics of the 51 patients with paraneoplastic encephalomyelitis (PEM) and Hu-Ab

Characteristicsn (%) or median (range)
Hu-Ab = anti-Hu antibodies; NSCLC = non-small cell lung cancer; Other = breast 2, colon 1, rectum 1; SCLC = small cell lung cancer.
Median age, y (range)62 (37–79)
Male sex41 (80.4)
Predominant syndrome
Sensory neuropathy34 (66.7)
Limbic encephalitis2 (3.9)
Brainstem/cerebellar5 (9.8)
Dysautonomia4 (7.8)
Multifocal6 (11.8)
Rankin score
0–336 (70.6)
4–515 (29.4)
Delay (mo) PEM to tumor diagnosis, median (range)5.3 (0–32)
Tumor type
SCLC42 (82.4)
NSCLC5 (9.8)
Other4 (7.8)
Immunotherapy25 (49.0)