Table 3.

Association between clinical characteristics and immunosuppressor or immunomodulating treatment in patients with paraneoplastic encephalomyelitis (PEM) and Hu-Ab

CharacteristicImmunotherapy, n (%)p Value
Yes, n = 25No, n = 26
Hu-Ab = anti-Hu antibodies; SCLC = small cell lung cancer; SSN = sensory neuropathy.
Median age, y (range)58 (37–73)68 (41–79)0.048
Rankin score
0–315 (60)21 (81.8)0.103
4–510 (40)5 (19.2)
Neurologic syndrome
SSN17 (68)17 (65.4)0.843
Other8 (32)9 (34.6)
Median delay (mo) in tumor diagnosis (range)5 (1–18)5 (0–32)0.60
Tumor type
SCLC21 (84)21 (81.8)0.526
Other4 (16)5 (19.2)
Tumor response
Complete15 (60)11 (42.3)0.206
Other10 (40)15 (57.7)
Median survival (mo)10.211.80.14