Table 3.

MRS results (NAA/Cr ratios; mean ± SE)

ParticipantsT1T2*
CingulateMotorCingulateMotor
* No bulbar-onset patients were able to complete T2 MRS owing to sialorrhea.
p < 0.05.
p < 0.001.
T1 = initial testing; T2 = testing 6 months after T1.
Bulbar onset1.77 ± 0.11.47 ± 0.1
Limb onset1.99 ± 0.072.09 ± 0.11.92 ± 0.021.76 ± 0.1
Control2.07 ± 0.032.27 ± 0.1