Table 2.

Sensitivity, specificity, positive predictive value, and negative predictive value of various clinical features for distinguishing patients with dementia with Lewy bodies (DLB) (“pure” and “mixed” DLB–Alzheimer’s disease cases) from patients without DLB

Clinical features	Any DLB, n = 18	Non-DLB dementia, n = 76	Sensitivity, %	Specificity, %	Positive predictive value, %	Negative predictive value, %	p Value
* Seven out of the nine pure DLB cases, five out of the nine DLB–Alzheimer’s disease cases, and 40 out of the 76 non-DLB cases were exposed to neuroleptics.
CDLB = Consortium on DLB.
CDLB criteria
Any 1 criterion	16	55	89	28	23	91	0.2
Any 2 criteria	11	12	61	84	48	90	0.0002
All 3 criteria	5	1	28	99	83	85	0.0008
Major criteria
Extrapyramidal signs	14	45	78	41	24	89	0.2
Fluctuations	10	18	56	76	36	88	0.02
Visual hallucinations	8	7	44	91	53	87	0.001
Minor criteria
Delusions	5	5	28	93	50	84	0.02
Falls	2	10	11	87	17	80	1
Neuroleptic sensitivity^*	7	6	39	92	54	86	0.002
Major or minor CDLB criteria
Any 1 criterion	16	58	89	24	22	90	0.3
Any 2 criteria	13	16	72	79	45	92	0.00008
Any 3 criteria	9	6	50	92	60	89	0.0001