Table 5.

Sensitivity, specificity, positive predictive value, and negative predictive value of various clinical features for distinguishing patients with pure dementia with Lewy bodies (DLB) from patients without pure DLB if analyses are confined to patients with mild to moderate dementia*

Clinical featuresPure DLB, n = 8Other dementia, n = 54Sensitivity, %Specificity, %Positive predictive value, %Negative predictive value, %p Value
* Mild to moderate dementia defined as score ≤20 on the Blessed test of information, orientation, and concentration.
CDLB = Consortium on DLB.
Major CDLB criteria
Any 1 criterion725885422970.05
Any 2 criteria710888141980.0002
All 3 criteria3038100100920.001
Major criteria
Extrapyramidal signs79888344980.0001
Fluctuations42509667930.001
Visual hallucinations47508736920.02
Minor criteria
Delusions35389138910.05
Falls1613891787NS
Neuroleptic sensitivity5063100100950.000008
Major or minor CDLB criteria
Any 1 criterion725885422970.05
Any 2 criteria713887635980.001
Any 3 criteria62759675960.00002