Sensitivity, specificity, positive predictive value, and negative predictive value of various clinical features for distinguishing patients with pure dementia with Lewy bodies from patients with Alzheimer’s disease and also if analyses are confined to patients with mild to moderate dementia*
| Clinical features | DLB, n = 9 | AD, n = 33 | Sensitivity, % | Specificity, % | Positive predictive value, % | Negative predictive value, % | p Value |
|---|---|---|---|---|---|---|---|
| * Mild to moderate dementia is defined as score ≤20 on the Blessed test of information, orientation, and concentration. | |||||||
| Consortium on Dementia with Lewy Bodies criteria | |||||||
| Any 1 criterion | 8 | 24 | 89 | 27 | 25 | 90 | 0.4 |
| Any 2 criteria | 7 | 12 | 78 | 64 | 37 | 91 | 0.05 |
| All 3 criteria | 4 | 1 | 44 | 98 | 80 | 90 | 0.001 |
| Combining any major or minor criteria* | |||||||
| Any 1 criterion | 7 /8 | 20 /30 | 88 | 33 | 26 | 91 | 0.4 |
| Any 2 criteria | 7 /8 | 13 /30 | 88 | 57 | 35 | 94 | 0.04 |
| Any 3 criteria | 6 /8 | 2 /30 | 75 | 93 | 75 | 93 | 0.0002 |