Table 1.

Clinical and electrophysiologic summary of different groups

CharacteristicSmall fiber sensory (Group 1)Large and small fiber sensory (Group 2)Axonal sensorimotor (Group 3)Demyelinating sensorimotor (Group 4)
Sensory conduction analysis was done in the sural nerve, and motor analysis was done on tibial and peroneal nerves.
CV = conduction velocity; EMG = electromyography.
Mean age, y (range)71 (65–78)60 (36–68)72 (60–80)62 (56–68)
Mean duration of illness, y (range)4.3 (1–12)4 (3–10)8.6 (3–23)7 (1–10)
Painful neuropathy, n (%)4/8 (50)3/5 (60)2/7 (28)1/3 (33)
Mean anti-sulfatide titers range124,800 (25,600–409,600)56,320 (25,600–102,400)179,000 (51,200–819,000)42,666 (25,600–51,200)
Monoclonal gammopathy, n (%)0/8 (0)2/5 (40)3/6 (50)2/3 (66)
Sensory CVNormalNormalNormalSlow
Sensory amplitudeNormalLowLowLow or absent
Motor CVNormalNormalNormal-borderlineSlow
Motor amplitudesNormalNormalLowLow or absent
Denervation on EMGAbsentRareMildRare