Table 4.

Summary of autopsy cases (n = 9)

No.Pathologic
ClinicalAge at death, yB&BCERADLBIVD/CVD scoresPathologic diagnosis
SexAge, ySxGroup
* Hippocampal sclerosis.
† Also showed demyelinating lesions consistent with MS.
Sx = symptomatic presentation; B&B = Braak & Braak staging; CERAD = Consortium to Establish a Registry for Alzheimer Disease; LB = Lewy Body score; IVD = ischemic vascular dementia; ad = Alzheimer-type changes confined to hippocampus; CVD = cerebrovascular disease; CN+L = cognitively normal with lacunes; Grad = gradually progressive dementia; CI+L = cognitively impaired with lacunes; D+L = dementia with lacunes.
1M75StrokeCN+L770None016/22IVD
2F74StrokeCN+L780005/7IVD
3F82NormalCN+L85IIIRare012/15IVD/ad
4M73NormalCN+L760007/11IVD
5M71StrokeCI+L71I–II*None019/24IVD
6F91GradD+L92II–III*Rare09/12IVD
7M79GradD+L80IIIModerate011/16IVD/ad
8W76GradD+L79IVModerate06/9IVD/ad
9M77GradD78I*Rare75/5DLB