Table 2.

Dyskinesia duration (Unified PD Rating Scale [UPDRS] item 32) and disability (UPDRS item 33) and dyskinesia scores during the levodopa challenge before and after surgery (mean ± SD)

Score (maximal value)Before surgery3-mo follow-up12-mo follow-upp Value
“Off” drug“On” drug“Off” stim“On” stim“Off” stim“On” stim
* p Value for the comparison between the preoperative score and the scores after surgery.
p Value for the comparison between the preoperative score and the “off”-stimulation condition at 3 and 12 months follow-up.
p Value for the comparison between the 3-month and the 12-month scores.
§ p Value for the comparison between the preoperative score and the “on”-stimulation condition at 3 and 12 months follow-up.
p Value for the comparison between the “off”-stimulation condition and the “on”-stimulation condition.
NA = not applicable; ND = not done.
Dyskinesia duration (4)NA1.8 ± 0.7NA0.4 ± 0.7NA0.4 ± 0.80.001*
Dyskinesia disability (4)NA2.7 ± 1.1NA0.6 ± 1.0NA0.2 ± 0.70.001*
“Off”-period dystonia (28)3.7 ± 2.9NA2.3 ± 1.81.4 ± 1.52.8 ± 2.91.3 ± 1.50.035; 0.011§; 0.03
Onset-of-dose dyskinesia (28)NA11.7 ± 4.86.1 ± 3.6ND3.6 ± 2.7ND0.001; 0.002
Peak-dose dyskinesia (28)NA10.9 ± 4.64.5 ± 2.95.6 ± 4.53.2 ± 2.42.9 ± 2.30.001; 0.06; 0.229