Table 4.

Adverse events as measured by percentage increases and 4-point severity scale

Adverse eventPlaceboOlanzapinep Value
UPDRS = Unified PD Rating Scale.
Mean percentage increase in
Percentage waking-day “off” time (diaries)2300.025
Percentage waking-day “off” time (UPDRS item 39)8300.075
UPDRS parts II & III5.718.70.043
Mean subjective rating on a 4-point scale
Increased “off” time0.221.220.059
Increased parkinsonism0.11.70.03
Drowsiness0.11.00.059
Overall adverse event impression0.11.70.01