Table 3.

CSF characteristics

CharacteristicsADEM (n = 26)MS (n = 14)p Value
* Significant.
ADEM = acute disseminated encephalomyelitis; Ig = immunoglobulin.
Leukocytes/μL, median (range)52 (3–472)20 (1–92)0.36
Normal CSF findings, n (%)5 (19)3 (21)0.87
Plasma cells present, n (%)17 (65)7 (50)0.50
Protein, g/L, median (range)0.63 (0.25–2.68)0.39 (0.15–0.76)0.11
Intrathecal synthesis
of IgG10 (38)8 (57)0.33
of IgM7 (27)1 (7)0.22
of IgA6 (23)1 (7)0.39
Blood–brain barrier disturbance, n (%)7 (23)1 (7)0.22
Albumin fraction, quotient CSF/ serum × 103, median (range)7.6 (2.4–28.8)4.3 (2.0–9.0)0.006*
Oligoclonal bands of IgG, n (%)15 (58)11 (80)0.30