Table 2.

Univariate associations between patient characteristics and response rate, median time to progression (TTP), and survival

Patient characteristicsCR, PR, or SD, %Progressive disease, %TTP, wkSurvival, wk
CR = complete response; PR = partial response; SD = stable disease.
Age, y
<40/≥4045 /3355 /6714 /1341 /30
KPS
≥90/<9075 /2325 /7726 /1344 /30
Prior histology
Lower grade tumor/GBM37 /3663 /6413 /1344 /30
Interval from initial diagnosis to recurrence ≥52/<52 wk36 /3764 /6313 /1336 /30