Table 3.

Multivariate analysis

CharacteristicsTime to progressionSurvival
Hazard ratio (95% CI)p ValueHazard ratio (95% CI)p Value
KPS = Karnofsky Performance Status; GBM = glioblastoma multiforme.
Age, y
<40 versus ≥ 400.53 (0.28–1.01)0.060.51 (0.25–1.03)0.06
KPS
≥90 versus <900.61 (0.34–1.10)0.100.64 (0.35–1.18)0.15
Prior histology
Lower grade tumor versus GBM0.93 (0.50–1.74)0.830.87 (0.47–1.62)0.67
Interval
≥52 versus <52 wk1.22 (0.69–2.15)0.490.89 (0.50–1.58)0.68