Table 1.

Characteristics of EVA MRI participants and correlates of grading of white matter hyperintensities

CharacteristicsTotal, n = 830Grade of white matter hyperintensitiesp Value
Mild, n = 319Moderate, n = 373Severe, n = 138
* Data are mean (SD).
† Reported history of angina pectoris or myocardial infarction or arteritis.
‡ Measured at baseline.
EVA = Epidemiology of Vascular Ageing.
Age at MRI examination, y*69.0 (2.9)68.5 (3.0)69.1 (2.8)69.7 (3.1)0.0001
Female sex, %58.254.561.158.70.22
Education level, y*10.7 (3.5)10.6 (3.4)10.8 (3.5)10.6 (3.5)0.81
History of vascular disease, %7.15.37.011.60.06
Systolic blood pressure, mm Hg*131 (18)130 (18)131 (17)135 (18)0.02
Diastolic blood pressure, mm Hg*79 (11)78 (11)78 (11)82 (12)0.003
Antihypertensive drug use, %25.821.323.941.30.0001
Daily alcohol consumption, %
0 glasses56.054.556.857.20.75
≤2 glasses27.727.021.228.3
>2 glasses16.318.515.014.5
Smoking status, %
Nonsmoker58.554.960.957.20.21
Ex-smoker33.338.230.332.6
Current smoker8.26.98.810.1