Table 2.

Multivariate association between baseline blood pressure (BP) and grading of white matter hyperintensities in the EVA MRI cohort*

BP measureGrade of white matter hyperintensities
Mild, n = 319, reference groupModerate, n = 373, OR (95% CI)Severe, n = 138, OR (95% CI)
* Adjusted for age, sex, and history of vascular disease.
† Per 1 SD increase.
EVA = Epidemiology of Vascular Ageing.
Systolic BP1.01.02 (0.87–1.20)1.32 (1.08–1.63)
Diastolic BP1.01.01 (0.92–1.12)1.19 (1.05–1.36)
Antihypertensive drug use1.01.12 (0.77–1.63)2.39 (1.53–3.72)
Hypertension1.01.06 (0.75–1.42)2.19 (1.43–3.36)