Table B7.

Therapeutic Breakout 7 Thalamotomy

Consistent and long-lasting improvement in contralateral tremor
May improve contralateral dyskinesia
Widely available; many surgeons have experience with the procedure
Necessitates needle passage(s) through the brain
No meaningful effect on the more disabling parkinsonian features (e.g., bradykinesia and gait dysfunction)
Necessitates making a lesion in the thalamus
Bilateral lesions associated with risk for severe dysarthria, dysphagia, and cognitive dysfunction