Mean (SD) magnetization transfer ratio (MTR) and mean diffusivity (D̄) histogram-derived metrics of brain tissue from patients with AD and control subjects
| Histogram metrics | Patients with AD | Control subjects | p Value* |
|---|---|---|---|
| * Statistical analysis: Student’s t-test for nonpaired data. | |||
| NS = not significant. | |||
| MTR, % | 38.4 (0.8) | 38.9 (0.9) | NS |
| MTR peak height, % | 93.2 (10.1) | 106.5 (7.9) | <0.001 |
| MTR peak location, % | 33.7 (1.5) | 34.0 (1.4) | NS |
| D̄, mm2s−1 × 10−3 | 1.05 (0.04) | 0.97 (0.05) | <0.001 |
| D̄ peak height, mm2s−1 × 10−3 | 75.7 (12.0) | 90.9 (8.6) | <0.001 |
| D̄ peak location, mm2s−1 × 10−3 | 0.80 (0.05) | 0.77 (0.05) | NS |