Mean (SD) magnetization transfer ratio (MTR) and mean diffusivity (D̄) histogram-derived metrics of cortical gray matter from patients with AD and control subjects
| Histogram metrics | Patients with AD | Control subjects | p Value* |
|---|---|---|---|
| * Statistical analysis: Student’s t-test for nonpaired data. | |||
| NS = not significant. | |||
| MTR, % | 36.8 (0.8) | 37.4 (1.1) | NS |
| MTR peak height, % | 81.6 (7.5) | 92.9 (6.2) | <0.001 |
| MTR peak location, % | 30.4 (2.1) | 31.6 (2.6) | NS |
| D̄, mm2s−1 × 10−3 | 1.21 (0.05) | 1.17 (0.06) | 0.01 |
| D̄ peak height, mm2s−1 × 10−3 | 43.5 (4.7) | 51.3 (6.2) | <0.001 |
| D̄ peak location, mm2s−1 × 10−3 | 0.98 (0.09) | 0.91 (0.06) | 0.02 |