Mean (SD) magnetization transfer ratio (MTR) and mean diffusivity (D̄) histogram-derived metrics of temporal lobe from patients with AD and control subjects
| Histogram metrics | Patients with AD | Control subjects | p Value* |
|---|---|---|---|
| * Statistical analysis: Student’s t-test for nonpaired data. | |||
| NS = not significant. | |||
| MTR, % | 37.0 (0.9) | 37.6 (0.9) | NS |
| MTR peak height, % | 86.3 (8.6) | 97.6 (6.9) | <0.001 |
| MTR peak location, % | 31.3 (2.6) | 32.1 (1.8) | NS |
| D̄, mm2s−1 × 10−3 | 1.23 (0.05) | 1.18 (0.05) | 0.03 |
| D̄ peak height, mm2s−1 × 10−3 | 43.4 (5.3) | 51.5 (6.9) | 0.001 |
| D̄ peak location, mm2s−1 × 10−3 | 0.97 (0.07) | 0.92 (0.05) | 0.01 |