Table 4.

Spearman rank correlations between MSFC and MRI measurements, when dividing the group by disease duration

Disease durationPFVFT1LVT2LV
* p < 0.05.
p < 0.01.
PF = parenchymal fraction: whole brain parenchyma/intracranial volume; VF = ventricular fraction: ventricle volume/whole brain parenchyma; T1LV = T1-weighted lesion volume; T2LV = T2-weighted lesion volume; MSFC = MS functional composite; EDSS = Expanded Disability Status Scale.
Duration of symptoms ≤5 y
    MSFC0.41*−0.27−0.41*−0.40*
    EDSS−0.35*0.200.190.21
Duration of symptoms >5 y
    MSFC0.33−0.33−0.10−0.15
    EDSS−0.160.16−0.15−0.12