Table 1.

Frequency of the TNFA-376 polymorphism

ClassificationMadrid, SpainOlmsted County, MN
Case, n (%)Control, n (%)OR (CI)*Case, n (%)Control, n (%)OR (CI)
NA = not applicable.
* χ2 or Fisher’s exact tests.
p Values are given for being a carrier for allele A.
Genotype
    GG198 (83.0)295 (91.0)0.49 (0.29–0.81)119 (98.3)237 (97.5)1.51 (0.30–7.58)
    GA40 (17.0)27 (8.0)2.23 (1.32–3.74)2 (1.7)6 (2.5)0.66 (0.13–3.34)
    AA02 (1.0)NA00NA
p = 0.003p = 0.999
Allele
    G436 (91.6)617 (95.2)1.00240 (99.2)480 (98.8)1.00
    A40 (8.4)31 (4.8)1.83 (1.12–2.97)2 (0.8)6 (1.2)0.67 (0.13–3.33)
p = 0.018p = 0.999
Carrier
    G238 (100)322 (99.4)1.00121 (100)243 (100)1.00
    A40 (16.8)29 (8.9)2.06 (1.23–3.43)2 (1.7)6 (2.5)0.66 (0.13–3.34)
p = 0.006p = 0.724