Table 2 Baseline to month 24 change in the MSFC and component Z-scores

TestPlacebo, n = 219IFNβ-1a, n = 217p Value*
* Analysis of covariance on ranks stratified on baseline EDSS and gadolinium enhancement on baseline MRI.
IFNβ-1a = interferon β-1a; MSFC = MS Functional Composite; T25FW = Timed 25-Foot Walk; 9HPT = Nine-Hole Peg Test; PASAT3 = Paced Auditory Serial Addition Test with a 3-second interstimulus interval.
MSFC
    Mean ± SD−0.495 ± 1.58−0.362 ± 1.41
    Median (midquartile range)−0.161 (−0.417 to 0.028)−0.096 (−0.305 to 0.066)0.033
T25FW
    Mean ± SD−1.191 ± 3.13−0.979 ± 2.62
    Median (midquartile range)−0.113 (−0.622 to −0.006)−0.076 (−0.402 to 0.00)0.378
9HPT
    Mean ± SD−0.290 ± 0.494−0.202 ± 0.476
    Median (midquartile range)−0.305 (−0.594 to 0.027)−0.169 (−0.457 to 0.105)0.024
PASAT3
    Mean ± SD−0.004 ± 0.473+0.094 ± 0.498
    Median (midquartile range)0.000 (−0.163 to 0.244)+0.081 (−0.081 to 0.244)0.061