Table 1 Brain volume and disability measurements at each time point
| Measure | Baseline | Year 1 | Year 2 | 8-Year follow-up |
|---|---|---|---|---|
| Values are expressed as mean (SD) [no. of patients]. | ||||
| EDSS = Expanded Disability Status Scale; MSFC = MS Functional Composite; BPF = brain parenchymal fraction. | ||||
| EDSS | 2.35 (0.84) [172] | 2.71 (1.37) [168] | 2.84 (1.57) [170] | 4.38 (2.33) [160] |
| MSFC | 0.0 (0.71) [171] | −0.10 (1.18) [163] | −0.11 (1.25) [150] | −1.05 (2.19) [135] |
| BPF | 0.830 (0.017) [137] | 0.824 (0.021) [152] | 0.821 (0.021) [148] | 0.804 (0.028) [134] |