Table 3 Logistic regression results for predicting EDSS ≥ 6
| Model no./variable | Regression coefficient | SE | p Value |
|---|---|---|---|
| * All risk factors at year 2, n = 126. | |||
| † All on-study changes, n = 125. | |||
| ‡ Year 2 MRI, n = 126. | |||
| § MRI on-study changes, n = 125. | |||
| EDSS = Expanded Disability Status Scale; MSFC = MS Functional Composite; BPF = brain parenchymal fraction. | |||
| 1* | |||
| Intercept | −2.75 | 0.74 | |
| EDSS (year 2) | 0.64 | 0.24 | 0.0070 |
| MSFC (year 2) | −0.98 | 0.39 | 0.012 |
| 2† | |||
| Intercept | −1.51 | 0.34 | |
| BPF change | −0.42 | 0.22 | 0.056 |
| MSFC change | −2.21 | 0.53 | <0.0001 |
| 3‡ | |||
| Intercept | 24.39 | 8.06 | |
| BPF (year 2) | −31.95 | 9.89 | 0.0012 |
| No. of relapses | 0.50 | 0.12 | <0.0001 |
| 4§ | |||
| Intercept | −2.15 | 0.37 | |
| BPF change | −0.45 | 0.18 | 0.0107 |
| No. of relapses | −0.42 | 0.11 | 0.0001 |