Table 3 Accuracy of dissemination in space definitions (Barkhof or two lesions and positive OB) and both combined in determining MS according to the Poser criteria

DefinitionCDMS
SensitivitySpecificityAccuracy
CDMS = clinically definite MS; DIS = dissemination in space; OB = oligoclonal bands.
DIS (Barkhof 3 or 4)716970
DIS (≥2 lesions plus OB)786367
DIS (Barkhof 3 or 4 or ≥2 lesions plus OB)875665