Table 1 Patient demographics and baseline characteristics

Characteristic25/50 mg topiramate (n = 125)200/500 mg topiramate (n = 127)
AED = antiepileptic drug.
Age, y, mean (range)36 (6–85)37 (6–79)
Age distribution, %  patients
    ≤16 y1811
    17–64 y6978
    ≥65 y1311
Sex, % male5053
Body weight ≤50 kg, % patients1811
Baseline partial-onset  seizures, % patients
    13829
    22419
    ≥33852
Time since first seizure, mo, median (range)7 (0–331)10 (0–312)
Time since diagnosis, mo, median (range)2 (0–132)2 (0–108)
Baseline AEDs, %  patients
    05756
    14143
    221