Table 3 Covariate analyses: median time-to-first seizure (days) in patient subgroups

Parameter25/50 mg Topiramate (n = 125)    200/500 mg  Topiramate  (n = 127)p Value*
* Log-rank test.
Baseline seizures
    ≤2 seizures146 (n = 78)>451 (n = 61)0.001
    ≥3 seizures52 (n = 47)78 (n = 66)0.871
Time since diagnosis
    ≤6 months140 (n = 87)>451 (n = 84)0.054
    >6 months84 (n = 37)84 (n = 43)0.778
Baseline AED
    No108 (n = 71)451 (n = 71)0.021
    Yes116 (n = 54)112 (n = 56)0.891