Table 3 Subtelomeric probe testing in children with global developmental delay

ReferenceClassLevel of mental retardationNNo. (%) of patients with significant rearrangements
Abnormalities were classified as significant if there was evidence that they caused retardation and nonsignificant when they appeared to be a polymorphism devoid of phenotypic consequences.
* Two patients had nonsignificant rearrangements.
† One additional patient had uniparental disomy.
68IControls750
Mild1821 (0.55)
Moderate/severe28421 (7.39)
69IControls150*0
Unspecified610
Mild820
Moderate/severe460
70IIUnspecified272 (7.4)
71IIModerate/severe292 (6.89)
72IIIQ < 6025413* (5.12)
73IIUnspecified1205 (4.17)
74IIMild440
Moderate/severe11713 (11.11)
75IIMild420
Moderate/severe281 (3.57)
76IIUnspecified503 (6.0)
77IIMild293 (10.3)
Moderate/severe827 (8.5)
78IIUnspecified2509 (3.6)