Table 2 Neurologic assessment at baseline: ITT cohort*

Neurologic assessmentOverall clinical impressionPlacebo, n = 77CR oxycodone, n = 82Total, n = 159
Values are n (%).
* Einstein Focused Neurologic Assessment.
† Rated on a four-point categorical scale. Scores for bilateral sites combined.
‡ Tested on the dorsal surface of the great toe, anterior malleolus, and head of fibula.
Distal sensory function
    Light touchNormal9 (11.7)4 (4.9)13 (8.2)
Mild7 (9.1)9 (11.0)16 (10.1)
Moderate38 (49.4)35 (42.7)73 (45.9)
Severe23 (29.9)34 (41.5)57 (35.8)
    Temperature (cold only)Normal11 (14.3)9 (11.0)20 (12.6)
Mild12 (15.6)14 (17.1)26 (16.4)
Moderate29 (37.7)31 (37.8)60 (37.7)
Severe25 (32.5)28 (34.1)53 (33.3)
    Sharp (pin)Normal12 (15.6)5 (6.1)17 (10.7)
Mild11 (14.3)16 (19.5)27 (17.0)
Moderate33 (42.9)35 (42.7)68 (42.8)
Severe21 (27.3)26 (31.7)47 (29.6)
Muscle strengthNormal51 (66.2)60 (73.2)111 (69.8)
Mild17 (22.1)19 (23.2)36 (22.6)
Moderate8 (10.4)3 (3.7)11 (6.9)
Severe1 (1.3)01 (<1%)
ReflexesNormal17 (22.1)10 (12.2)27 (17.0)
Mild19 (24.7)19 (23.2)38 (23.9)
Moderate30 (39.0)38 (46.3)68 (42.8)
Severe11 (14.3)15 (18.3)26 (16.4)