Table 1 Demographic and disease-related variables in the ALS autopsy cohort
| Diagnosis | No. | Age, y, mean (SE) | Sex ratio, M:F | Age at onset, y, mean (SE) | Disease duration, mo, mean (SE) | Interval from last assessment, d, range |
|---|---|---|---|---|---|---|
| All comparisons between disease categories are nonsignificant. | ||||||
| * Two cases with a pure lower motor neuron (LMN) disorder were excluded from the analysis because of the absence of typical ALS-type ubiquinated LMN inclusions in LMN. | ||||||
| PMA = progressive muscular atrophy; PMA→ALS = PMA presentation later developing typical ALS. | ||||||
| PMA* | 10 | 64.3 (3.1) | 6:4 | 63.0 (3.2) | 16.2 (1.9) | 2–90 |
| PMA→ALS | 6 | 68.8 (5.7) | 4:2 | 66.7 (5.7) | 25.7 (5.9) | — |
| ALS | 63 | 64.5 (1.4) | 32:31 | 63.4 (1.6) | 22.5 (1.8) | — |