Table Clinical characteristics (mean ± sd) of patients with Huntington’s disease (HD)
| Baseline measures | CAPIT-HD short battery (full cohort of n = 61) | CAPIT-HD baseline tests (subset of n = 34) | CANTAB battery (subset of n = 21) |
|---|---|---|---|
| Unified Huntington’s Disease Rating Scale (UHDRS) motor score provides an indication of motor impairment (higher scores for greater impairment, maximum score of 124). Total Functional Capacity score comprises items that assess the ability to perform activities of daily living (lower scores indicate greater impairment, maximum score of 15). Independence scale provides a measure of overall functional ability (lower scores indicate greater impairment, maximum score of 100). | |||
| CAPIT-HD = Core Assessment Program for Intracerebral Transplantation in HD; CANTAB = Cambridge Neuropsychological Test Automated Battery. | |||
| Male/female | 40/21 | 24/10 | 15/6 |
| Paternal/maternal/not known transmission of HD gene | 27/29/5 | 18/13/3 | 14/6/1 |
| Follow-up duration, y | 4 ± 1 | 3 ± 1 | 5 ± 1 |
| Number of assessments | 4.08 ± 0.94 | 2 ± 0.0 | 4.52 ± 1.08 |
| Age, y | 45.7 ± 9.0 | 44.9 ± 8.1 | 47.2 ± 10.7 |
| Duration of HD since first symptoms, y | 4.3 ± 3.7 | 4.3 ± 4.1 | 4.5 ± 3.4 |
| UHDRS motor score | 29.4 ± 17.6 | 31.0 ± 18.3 | 25.1 ± 14.2 |
| Total Functional Capacity | 9.7 ± 2.6 | 9.5 ± 2.5 | 9.9 ± 2.4 |
| Independence scale | 87.8 ± 12.3 | 87.1 ± 11.0 | 92.1 ± 10.4 |