Table 4. Clinically isolated syndromes characteristic of MS
| Syndrome | Features |
|---|---|
| Optic neuritis | 1. Typically unilateral |
| 2. Retrobulbar | |
| 3. Typically painful | |
| 4. Some recovery expected | |
| 5. No retinal exudates | |
| 6. No macular star | |
| 7. Disc hemorrhages infrequent | |
| Myelitis | 1. Partial sensory or motor |
| 2. Sensory more common | |
| 3. Lhermitte sign | |
| 4. Bowel and bladder dysfunction is common | |
| 5. “Band-like” abdominal or chest pressure | |
| 6. Acute dystonias | |
| Brainstem/cerebrum | 1. Ocular motor syndromes (e.g., internuclear ophthalmoparesis/nystagmus) |
| 2. Hemisensory, crossed sensory syndromes | |
| 3. Hemiparesis | |
| 4. Trigeminal neuralgia | |
| 5. Hemifacial spasm | |
| Cerebellum | 1. Cerebellar outflow tremor |
| 2. Acute ataxic syndrome | |
| Paroxysmal | 1. Tonic spasms |
| symptoms | 2. Paroxysmal dysarthria/ataxia |