Table 3 Comparison of outcomes in migraine patients and controls (95% CI)

OutcomesTM vs CTMNM vs CNMAll migraine vs all controls
* Adjusted for hypertension, diabetes, cardiac disease, obesity, hypercholesterolemia, oral contraceptive use, and smoking status.
† Adjusted for hypertension, diabetes, obesity, hypercholesterolemia, oral contraceptive use, and smoking status.
‡ Insufficient numbers for adjusted analysis.
TM = triptan-treated migraine; CTM = controls for triptan-treated migraine; NM = non-triptan-treated migraine; CNM = controls for non-triptan-treated migraine; MI = myocardial infarction; IHD = non-MI ischemic heart disease.
Stroke
    Crude incidence rate ratio1.11 (0.75, 1.63)1.63 (1.35, 1.96)1.59 (1.35, 1.87)
    Adjusted hazard ratio*1.13 (0.78, 1.65)1.51 (1.26, 1.82)1.52 (1.29, 1.78)
MI
    Crude incidence rate ratio0.87 (0.55, 1.35)1.17 (0.95, 1.44)1.16 (0.97, 1.40)
    Adjusted hazard ratio0.93 (0.60, 1.43)1.11 (0.91, 1.36)1.15 (0.96, 1.38)
IHD
    Crude incidence rate ratio1.27 (1.00, 1.60)1.35 (1.18, 1.54)1.36 (1.22, 1.52)
    Adjusted hazard ratio*1.22 (0.96, 1.53)1.24 (1.09, 1.41)1.29 (1.15, 1.44)
Ventricular arrhythmias
    Crude incidence rate ratio0.77 (0.07, 4.68)1.46 (0.52, 4.46)1.23 (0.52, 2.95)
All-cause mortality
    Crude incidence rate ratio0.75 (0.59, 0.94)0.75 (0.67, 0.83)0.79 (0.72, 0.87)
    Adjusted hazard ratio*0.81 (0.65, 1.01)0.72 (0.65, 0.80)0.76 (0.70, 0.84)
Cardiovascular mortality
    Crude incidence rate ratio0.83 (0.47, 1.44)0.79 (0.63, 0.98)0.86 (0.70, 1.06)
    Adjusted hazard ratio0.99 (0.57, 1.70)0.83 (0.66, 1.03)0.93 (0.76, 1.13)