Table 2 Summary of AAN evidence-based guidelines level A or B recommendation for use*

DrugPartial adjunctive adultPartial monotherapyPrimary generalizedSymptomatic generalizedPediatric partial
* NB: In a previous parameter, felbamate was recommended for intractable partial seizures in patients over age 18 and patients over 4 with the Lennox-Gastaut syndrome. Felbamate is associated with significant and specific risks, and risk-benefit ratio must be considered.3
† Not Food and Drug Administration approved for this indication.
GabapentinYesNoNoNoYes
LamotrigineYesYesNoYesYes
TopiramateYesYesYes (only generalized tonic-clonic)YesYes
TiagabineYesNoNoNoNo
OxcarbazepineYesYesNoNoYes
LevetiracetamYesNoNoNoNo
ZonisamideYesNoNoNoNo