Table Demographics and relevant clinical variables of six DBS-treated suicide patients

VariablePatient
1323456
DBS = deep brain stimulation; GPi = globus pallidus pars interna; STN = subthalamic nucleus; Voa = (nucleus) ventralis oralis anterior; Vim = (nucleus) ventralis intermediate medial; PD = Parkinson disease; ET = essential tremor; UPDRS = Unified Parkinson’s Disease Rating Scale; UDRS = Unified Dystonia Rating Scale.
GenderMMMMMF
Neurologic conditionPostanoxic generalized dystoniaPDPDPDPDET
Age at disease onset, y203428512417
Age at death, y265141715069
Previous DBSGPiGPiGPiNoneGPiNone
DBS site at time of deathVoaSTNSTNSTNGPi + STNVim
    0 1 2 3. − − .… −. . − .. − . .− …− . . +
. −− .
    Right side
        V3.23.03.53.71.83.5
1.9
        μs450902109060210
90
DBS parameters at time of death
    Hz130130130185130130
185
    0 1 2 3. − − .… −. . − .. − . .− …
− …
    Left side
        V3.22.33.253.51.8Off
2.7
        μs450602109090
90
        Hz130130130185130
185
Electrode location at MRI scan and/or autopsyAt target for both sidesAt target for both sidesAt target for both sidesAt targetAt target for both sidesAt target
Time interval between last DBS surgery and suicide, y0.3332427
Medications for movement disorders at time of deathYesNoYesYesNoNo
UPDRS Part III score near time of death33 (UDRS)4201810NA
Past or present psychiatric featuresDepression, aggressive behaviorDepression, anxiety, euphoria, mania, irritabilityDepression, hallucinations, paranoia, compulsive behaviorNoneBipolar mood disorderDepression
Suicide ideations or attempts prior to DBSYesNoYesNoNoNo
Method of suicideHangingDefenestrationDrug overdoseDefenestrationEuthanasia groupEuthanasia group
Antidepressants or psychiatric support at time of deathNoYesYesNoYesYes
Other potential favoring factors for suicidePrevious drug dependencyNoneNoneBlindness, chronic painChronic painMeige syndrome
Cognitive dysfunction near time of deathExecutive dysfunction, memory deficitsNoneExecutive dysfunction, memory deficitsVisuospatial and executive dysfunctionsNoneNone