Table 3 Pooled relative risk of having a migraine associated with vomiting, nausea, or aura on or between day 1 ± 5 days of menstruation and on or between day 1 ± 2 days of menstruation

Migraine associated with1st day of menstruation ± 5 days1st day of menstruation ± 2 days
Relative risk95% CISignificanceNo. of women*Relative risk95% CISignificanceNo. of women
Premenstruation is the 5 (or 2) days before menstruation; menstruation is the 1st day of bleeding and the subsequent 5 (or 2) days.
* The number of women on whom the relative risk is based.
† “All other times” is defined as the days of the cycle other than day 1 of menstruation ± 5 days.
Vomiting
    Premenstruation1.550.67–3.24p = 0.33212.620.87–6.31p = 0.0919
    Menstruation3.091.82–5.28p < 0.0001244.692.62–8.31p < 0.000122
    All other times1.001.00
Nausea
    Premenstruation1.290.98–1.66p = 0.07681.841.30–2.53p < 0.000166
    Menstruation2.181.81–2.63p < 0.0001702.602.08–3.23p < 0.000169
    All other times1.001.00