Table 2 1H MR spectroscopy metabolite ratios (mean ± SD) in normal subjects and patients with AD, FTLD, DLB, and VaD

NormalADFTLDDLBVaD
Metabolite ratios were different from normal on Dunett test: * p = 0.08;
p = ≤ 0.05);
p ≤ 0.01;
§ p < 0.001.
AD = Alzheimer disease; FTLD = frontotemporal lobar dementia; DLB = dementia with Lewy bodies; VaD = vascular dementia; NAA = N-acetylaspartate; Cr = creatine; Cho = choline; MI = myo-inositol.
n20612141208
NAA/Cr (range)1.53 ± 0.131.42 ± 0.12§1.43 ± 0.15§1.53 ± 0.131.43 ± 0.13*
(1.07–1.93)(1.11–1.67)(1.13–1.78)(1.23–1.78)(1.27–1.69)
Cho/Cr (range)0.66 ± 0.080.69 ± 0.080.70 ± 0.080.73 ± 0.100.69 ± 0.11
(0.49–0.95)(0.45–0.91)(0.55–0.92)(0.61–0.92)(0.52–0.90)
MI/Cr (range)0.65 ± 0.080.73 ± 0.11§0.76 ± 0.09§0.69 ± 0.110.64 ± 0.08
(0.32–0.89)(0.40–0.97)(0.56–1.00)(0.55–0.92)(0.51–0.79)